Business View Civil and Municipal | September 2022

115 CIVIL AND MUNICIPAL VOLUME 3, ISSUE 9 Revolutionizing Antibody Discovery With visionary antibody technologies and straightforward business terms, our team of highly collaborative, creative, hard-working scientists is focused on empowering companies in the field of antibody drug discovery to generate antibody drugs against any target, to create cures for any disease. We do this by selecting antibodies from our in-house Generation 3 Antibody Library Platform, optimizing antibodies provided by partners, or by building and transferring our library platform to companies preferring to carry out discovery internally. Each Platform Specifica provides to a partner is exclusive to that partner, created from unique donor sets not used for any other partner, and constructed de novo. Specifica has an active research and development program, always optimizing and improving its libraries, as well as developing novel antibody library formats and selection tools. Generation 3 Platform Specifica’s Generation 3 Library Platform has quality built in by design. Developability, extremely high diversity, and the exclusion of sequence liabilities are intrinsic to the four sub-libraries making up the Platform, each of which is based on a therapeutic antibody scaffold chosen for excellent biophysical properties, lack of liabilities and germline gene variety. Specifica also creates custom antibody libraries based on partner preferences. As diversity is all derived from natural antibody binding loops which Specifica retains, the same unique partner diversity can be repackaged into many different antibody formats. Our Santa Fe HQ Specifica’s new headquarters were completed in June 2021 at the heart of the vibrant Railyard district of Santa Fe, New Mexico. Our spacious new facility has greatly expanded our capacity to develop, build and deliver our Generation 3 Antibody Library Platforms, as well as provide our discovery and optimization services – all with the highest level of quality and punctuality. Outfitted with state-of-the-art instrumentation, equipment and safeguards, our laboratories were designed by our science and architectural teams to optimize our workflows, with an overriding objective to align workspaces with our mission to successfully transfer our technology to the world’s top antibody discovery companies, including Bayer, UCB and Sanofi. Our laboratory workstations are project-dedicated and self-sufficient, including UV irradiation systems and room- dedicated HVAC systems to ensure a sterile environment free of cross contamination. In this thoroughly modern design, the work spaces link together to create a harmonious and flowing environment, full of natural light, views of the mountains and the Santa Fe Railyard Farmer’s Market. Truly an inspiring atmosphere for discovery. ...... For more information, please visit our website www.specifica.bio